![]() ![]() ![]() adults between 45 and 75 years showed that, of the people taking aspirin, 81% were taking aspirin for primary prevention of cardiovascular disease. 5 The American Heart Association and American Stroke Association's guidelines on primary prevention of stroke give a moderate IIa recommendation for aspirin's use in primary prevention of stroke in high risk groups. 4 The guidelines are based on interpretation of previous meta-analytic findings, which report a modest benefit for selected high risk patients, mostly related to a small absolute reduction in non-fatal myocardial infarctions in elderly patients, which is offset by an increased risk of major gastrointestinal and hemorrhagic stroke. 2 While a large number of the general population elect to take a daily aspirin for primary prevention of stroke, 3 there is disagreement in current guidelines about the use of aspirin for primary prevention. ![]() Aspirin has been shown to be effective for secondary prevention post myocardial infarction and stroke, 1 but there is uncertainty about its role in primary prevention populations, including those with cardiovascular risk factors (e.g. ![]()
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